The Pencil Code is a highly modular physics-oriented simulation code that can be adapted to a wide range of applications. It is primarily designed to solve partial differential equations (PDEs) of compressible hydrodynamics and has lots of add-ons ranging from astrophysical magnetohydrodynamics (MHD) to meteorological cloud microphysics and engineering applications in combustion. Nevertheless, the framework is general and can also be applied to situations not related to hydrodynamics or even PDEs, for example when just the message passing interface or input/output strategies of the code are to be used. The code can also evolve Lagrangian (inertial and noninertial) particles, their coagulation and condensation, as well as their interaction with the fluid.